Delay discounting is associated with treatment response among cocaine-dependent outpatients.
نویسندگان
چکیده
منابع مشابه
Delay discounting of cocaine by rhesus monkeys.
The present, subjective value of a reinforcer typically decreases as a function of the delay to its receipt, a phenomenon termed delay discounting. Delay discounting, which is assumed to reflect impulsivity, is hypothesized to play an important role in drug abuse. The present study examined delay discounting of cocaine injections by rhesus monkeys. Subjects were studied on a discrete-trials tas...
متن کاملα2A -Adrenergic receptor polymorphisms and mRNA expression levels are associated with delay discounting in cocaine users.
Cocaine users characteristically display preferences for smaller immediate rewards over larger delayed rewards, and this delay discounting (DD) has been proposed as an endophenotype of cocaine addiction. Recent evidence suggests that the norepinephrine system and more specifically the α2A -adrenergic receptor (ADRA2A) are impacted by chronic cocaine use while also being potentially involved in ...
متن کاملCommunity reinforcement therapy for cocaine-dependent outpatients.
OBJECTIVE To examine the contributions of community reinforcement therapy to outcome in the community reinforcement approach (CRA) + vouchers outpatient treatment for cocaine dependence. METHODS One hundred cocaine-dependent outpatients were randomly assigned to one of 2 treatment conditions: CRA + vouchers or vouchers only. All patients earned incentives in the form of vouchers exchangeable ...
متن کاملAnticipatory reward processing among cocaine-dependent individuals with and without concurrent methadone-maintenance treatment: Relationship to treatment response.
BACKGROUND Cocaine dependence among opioid-dependent methadone-maintained individuals is a significant public health problem and is particularly challenging to treat. The neurobiology of this clinically complex population has not been previously assessed using fMRI. METHODS fMRI data from cocaine-dependent, methadone-maintained (CD-MM) patients (n=24), cocaine-dependent (CD) patients (n=20) a...
متن کاملLetting go of the present: mind-wandering is associated with reduced delay discounting.
The capacity to self-generate mental content that is unrelated to the current environment is a fundamental characteristic of the mind, and the current experiment explored how this experience is related to the decisions that people make in daily life. We examined how task-unrelated thought (TUT) varies with the length of time participants are willing to wait for an economic reward, as measured u...
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ژورنال
عنوان ژورنال: Experimental and Clinical Psychopharmacology
سال: 2011
ISSN: 1936-2293,1064-1297
DOI: 10.1037/a0023617